Aquaporin 2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityAquaporin 2
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Formatimmunogen affinity purified
Size0.1 mg
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunohistochemistry (IHC) Formalin
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DescriptionDescription: Rabbit IgG polyclonal antibody for Aquaporin-2(AQP2) detection. Tested with WB, IHC-P, IHC-F in Human, Mouse, Rat. Background: AQP2(Aquaporin 2) also called AQUAPORIN-CD, is found in the apical cell membranes of the kidney's collecting duct principal cells and in intracellular vesicles located throughout the cell. The AQP2 gene is mapped to chromosome 12q13, very close to the site of major intrinsic protein by situ hybridization. The investigators suggested that a defect in the AQP2 gene is the basis of the autosomal form of nephrogenic diabetes insipidus. The functional expression and the limited localization suggested that AQP2 is the vasopressin-regulated water channel. Using rat kidney slices and porcine kidney cells stably
ImmunogenImmunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Aquaporin 2 (245-260aa DWEEREVRRRQSVELH), identical to the related rat and mouse sequences.
Other Names[Aquaporin-2(AQP-2); aquaporin 2(collecting duct); ADH water channel; AQP 2; AQP CD; AQP-2; AQP-CD; AQP2; AQP2_HUMAN; AQPCD; Aquaporin 2 collecting duct; Aquaporin CD; Aquaporin-2; Aquaporin-CD; Aquaporin2; Aquaporine 2; Collecting duct water channel protein; MGC34501; Water channel aquaporin 2; Water channel protein for renal collecting duct; WCH CD; WCH-CD; WCHCD], [AQP2; AQP2; AQP-CD; WCH-CD; AQP-2; AQP-CD]
Gene, Accession #[AQP2], Gene ID: 359, NCBI: P41181.1, UniProt: P41181
Catalog #MBS175560
Order / More InfoAquaporin 2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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