PKC zeta (Phospho-Thr560) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | PKC zeta (Phospho-Thr560) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | epitope affinity purified |
| Size | 0.05 mL, 0.1 mL |
| Concentration | 1.0 mg/ml |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The antibody detects endogenous level of PKC zeta only when phosphorylated at threonine 560. This is a calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. Essential for T-cell receptor (TCR)-mediated T-cell activation, but is dispensable during TCR-dependent thymocyte development. Links the TCR signaling complex to the activation of NF-kappa-B in mature T lymphocytes. Required for interleukin-2 (IL2) production. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters. |
| Immunogen | Immunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around phospho rylation site of threonine560(Q-L-T(p)-P-D) derived from Human PKC zeta. |
| Other Names | [KPCZ; PKC-zeta; PKC2; PRKCZ; nPKC-zeta] |
| Gene, Accession # | [PKC zeta], Gene ID: 5590, NCBI: NP_001028753.1, UniProt: Q05513 |
| Catalog # | MBS9412001 |
| Price | $200, $255 |
| Order / More Info | PKC zeta (Phospho-Thr560) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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