Zap-70 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Zap-70 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | Zap-70 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit polyclonal to Human Zap-70. The Syk family protein tyrosine kinase Zap-70 is expressed in T and NK cells and plays a critical role in mediating T cell activation in response to T cell receptor (TCR) engagement (1). Following TCR engagement, Zap-70 is rapidly phosphorylated on several tyrosine residues through autophosphorylation and transphosphorylation by the Src family tyrosine kinase Lck (2-6). Tyrosine phosphorylation correlates with increased Zap-70 kinase activity and downstream signaling events. Expression of Zap-70 is correlated with disease progression and survival in patients with chronic lymphocytic leukemia (7,8). |
| Immunogen | Immunogen: A fusion protein of human Zap-70 |
| Other Names | [ZAP70; Zap-70; Zap-70; ZAP70; FLJ17670; FLJ17679; SRK; STD; TZK; ZAP-70;], [ZAP70; ZAP70; SRK; STD; TZK; STCD; ZAP-70; SRK] |
| Gene, Accession # | Gene ID: 7535, NCBI: NP_001070.2, UniProt: P43403 |
| Catalog # | MBS125722 |
| Price | $275, $430 |
| Order / More Info | Zap-70 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Chu, D.H. et al. (1998) Immunol. Rev. 165, 167-180. 2. Iwashima, M. et al. (1994) Science 263, 1136-1139. 3. Neumeister, E.N. et al. (1995) Mol. Cell Biol. 15, 3171-3178. 4. Chan, A.C. et al. (1995) EMBO J. 14, 2499-2508. 5. Williams, B.L. et al. (1999) EMBO J. 18, 1832-1844. 6. Di Bartolo, V. et al. (1999) J. Biol. Chem. 274, 6285-6294. 7. Wiestner, A. et al. (2003) Blood 101, 4944-4951. 8. Crespo, M. et al. (2003) N. Engl. J. Med. 348, 1764-1775. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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