Edit |   |
---|---|
Antigenic Specificity | BMP-8 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: BMP-8 Polyclonal Antibody detects endogenous levels of BMP-8 protein. BMP8B (bone morphogenetic protein 8b) encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The encoded protein stimulates thermogenesis in brown adipose tissue. Expression of BMP8B may be downregulated in pancreatic cancer. BMP8B may have arose from a gene duplication event and its gene duplicate is also present on chromosome 1. |
Immunogen | Immunogen: Synthesized peptide derived from the internal region of human BMP-8 |
Other Names | [Rabbit BMP-8; BMP8B; BMP8; Bone morphogenetic protein 8B; BMP-8; BMP-8B; Osteogenic protein 2; OP-2; BMP8A; Bone morphogenetic protein 8A; BMP-8A] |
Gene, Accession # | [BMP-8], Gene ID: 656, NCBI: NP_001711.2, UniProt: P34820 |
Catalog # | MBS9706857 |
Price | $130, $220, $325 |
Order / More Info | BMP-8 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |