MAP3K2 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | MAP3K2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: MAP3K2 antibody detects endogenous levels of MAP3K2. Function: Component of a protein kinase signal transduction cascade. Regulates the JNK and ERK5 pathways by phosphorylating and activating MAP2K5 and MAP2K7 (By similarity). Plays a role in caveolae kiss-and-run dynamics.Subunit Structure: Interacts with PKN2; the interaction activates PKN2 kinase activity in a MAP3K2-independent kinase activity (By similarity). Self-associates. Binds both upstream activators and downstream substrates in multimolecular complexes. Interacts (via the kinase catalytic domain) with STK38. Interacts with XIAP/BIRC4.Post-translational Modifications: Autophosphorylated. Ubiquitination by XIAP/BIRC4 does not lead to proteasomal degradation. |
| Immunogen | Immunogen: A synthesized peptide derived from human MAP3K2 Subcellular Location: Nucleus |
| Other Names | [M3K2_HUMAN; Map3k2; MAPK/ERK kinase kinase 2; MEK kinase 2; MEKK 2; MEKK2b; Mitogen activated protein kinase kinase kinase 2; Mitogen-activated protein kinase kinase kinase 2] |
| Gene, Accession # | [MAP3K2], Gene ID: 10746, NCBI: NP_006600.3, UniProt: Q9Y2U5 |
| Catalog # | MBS9603194 |
| Price | $240, $280 |
| Order / More Info | MAP3K2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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