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Antigenic Specificity | IL-36B |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: IL-36B antibody is human specific. At least two isoforms of IL-36B are known to exist; this antibody will only detect the longer isoform. IL-36B antibody will not cross-react with IL-36A or IL-36G. IL-36B is is a member of the interleukin 1 cytokine family whose gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2 (1). IL-36B is thought to activate the NF-kappaB pathway through IL-1 receptor family members IL-1RL2 and IL-1RAcP (2). Like the related proteins IL-36A and IL-36G, IL-36B requires post-translational processing for full agonist activity, but the cleavage mechanism is currently unknown (3). The IL-36 cytokines have been suggested to amplify Th1 responses by enhancing proliferatio |
Immunogen | Immunogen: IL-36B antibody was raised against a 16 amino acid peptide near the carboxy terminus of human IL-36B. Buffer: IL-36B antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [IL-36B; FIL1; FIL1H; IL1F8; IL1H2; IL-1F8; IL-1H2; IL1-ETA; FIL1-(ETA); FILI-(ETA); Interleukin-36 beta; FIL1 eta; IL-1 eta; interleukin 36, beta], [IL36B; IL36B; FIL1; FIL1H; IL1F8; IL1H2; IL-1F8; IL-1H2; IL1-ETA; FIL1-(ETA); FILI-(ETA); IL1F8; IL1H2; IL-1 eta; IL-1F8; IL-1H2] |
Gene, Accession # | [IL36B], Gene ID: 27177, NCBI: NP_055253, UniProt: Q9NZH7 |
Catalog # | MBS153331 |
Price | $375 |
Order / More Info | IL-36B Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |