Heparin Cofactor II Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHeparin Cofactor II
Clonepolyclonal
Host SpeciesGoat
Reactive Speciesdog, human, mouse, porcine, rabbit, rat
Isotypen/a
Formatperoxidase (HRP) conjugate
Size0.1 mg
Concentrationn/a
ApplicationsELISA (EL/EIA)
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DescriptionRecognizes human Heparin Cofactor II. Heparin Cofactor II (HCII) is a single chain glycoprotein produced in the liver and circulates in plasma at concentration of 50-100ug/ml (0.8-1.5uM). A member of the SERPIN family of proteinase inhibitors, HCII exhibits a relatively narrow specificity and is only known to inhibit the serine proteinases thrombin and chymotrypsin. The inhibitory activity toward thrombin is accelerated up to 1000-fold in the presence of optimal concentrations of heparin. Unlike Antithrombin, thrombin inhibition by HCII is also enhanced by dermatan sulphate. HCII has an apparent molecular weight of 65,600 daltons and interaction with thrombin results in a covalent 1:1 enzyme-inhibitor complex of 102,600 daltons (1-3).
ImmunogenImmunogen: Heparin Cofactor II isolated from human plasma.
Other Names[-Heparin Cofactor II (HRP) (HCII)], [SERPIND1; SERPIND1; HC2; LS2; HCF2; HCII; HLS2; D22S673; HCF2]
Gene, Accession #Gene ID: 3053, UniProt: P05546
Catalog #MBS614799
Price$540
Order / More InfoHeparin Cofactor II Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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