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Antigenic Specificity | HLA-DQB1/2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: HLA-DQB1/2 Polyclonal Antibody detects endogenous levels of HLA-DQB1/2 protein. HLA-DQB1 belongs to the HLA class II beta chain paralogs. This class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: b lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and it contains six exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DQ molecu |
Immunogen | Immunogen: Synthesized peptide derived from the internal region of human HLA-DQB1/2 |
Other Names | [Rabbit HLA-DQB1/2; HLA-DQB1; HLA-DQB; HLA class II histocompatibility antigen, DQ beta 1 chain; MHC class II antigen DQB1; HLA-DQB2; HLA-DXB; HLA class II histocompatibility antigen, DQ beta 2 chainHLA class II histocompatibility antigen, DX beta chain; MHC class II antigen DQB2] |
Gene, Accession # | [HLA-DQB1/2], Gene ID: 3119, NCBI: NP_001230891.1, UniProt: P01920 |
Catalog # | MBS9703874 |
Price | $130, $220, $325 |
Order / More Info | HLA-DQB1/2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |