RTP801 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | RTP801 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mg |
| Concentration | 1 mg/mL |
| Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | RTP801 Antibody: RTP801 was initially identified as a gene induced by DNA damage, and later found to also be regulated by other cellular stresses such as hypoxia and glucocorticoid treatment. Recently, RTP801 has been shown to act as a mediator of tuberous sclerosis complex (TSC)-dependent regulation of the mammalian Target of Rapamycin (mTOR), an evolutionarily conserved serine/threonine kinase that regulates cell growth and cell cycle. In response to energy stress, RTP801 inhibits mTOR function, resulting in dephosphorylation of downstream targets such as ribosomal protein S6 kinase 1 and 4EBP1 and decreasing cell growth. Disregulation of RTP801 may thus contribute to human tumorigenesis. |
| Immunogen | Immunogen: RTP801 antibody was raised against a 12 amino acid synthetic peptide from near the center of human RTP801. Buffer: RTP801 Antibody is supplied in PBS containing 0.02% sodium azide. |
| Other Names | [RTP801; Dig2; REDD1; REDD-1; RTP801; DNA damage-inducible transcript 4 protein; HIF-1 responsive protein RTP801; DNA-damage-inducible transcript 4], [DDIT4; DDIT4; Dig2; REDD1; REDD-1; REDD1; RTP801; REDD-1] |
| Gene, Accession # | [DDIT4], Gene ID: 54541, NCBI: NP_061931, UniProt: Q9NX09 |
| Catalog # | MBS151232 |
| Price | $375 |
| Order / More Info | RTP801 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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