HLA-DMA Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHLA-DMA
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
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DescriptionSpecificity: HLA-DMA antibody detects endogenous levels of total HLA-DMA. Function: Plays a critical role in catalyzing the release of class II-associated invariant chain peptide (CLIP) from newly synthesized MHC class II molecules and freeing the peptide binding site for acquisition of antigenic peptides. In B-cells, the interaction between HLA-DM and MHC class II molecules is regulated by HLA-DO.Subunit Structure: Heterodimer of an alpha chain (DMA) and a beta chain (DMB).Similarity: Belongs to the MHC class II family.
ImmunogenImmunogen: A synthesized peptide derived from human HLA-DMA Subcellular Location: Late Endosome Membrane; Single-Pass Type I Membrane Protein. Lysosome Membrane; Single-Pass Type I Membrane Protein. Note: Localizes to late endocytic compartment. Associates with lysosome membranes.
Other Names[Class II histocompatibility antigen M alpha chain; D6S222E; DMA; HLA class II histocompatibility antigen DM alpha chain; HLA DMA; HLADM; Major histocompatibility complex class II DM alpha; MHC class II antigen DMA; OTTHUMP00000029242; OTTHUMP00000062997; OTTHUMP00000178727; OTTHUMP00000178728; OTTHUMP00000178729; Really interesting new gene 6 protein; Ring 6; Ring6]
Gene, Accession #[HLA-DMA], Gene ID: 3108, NCBI: P28067.1, UniProt: P28067
Catalog #MBS9609889
Price$240, $280
Order / More InfoHLA-DMA Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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