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Antigenic Specificity | CDC25C |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human, mouse |
Isotype | IgG1 |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: CDC25C antibody detects endogenous levels of total CDC25C. Description: A member of the MPI phosphatase family. Activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. Shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. At least four transcript variants for this gene exist. Three splice variant isoforms have been described.Function: Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phos |
Immunogen | Immunogen: Purified recombinant fragment of human CDC25C expressed in E. Coli Subcellular Location: Nucleus. Tissue Specificity: Expressed predominantly in G2 phase. |
Other Names | [CDC 25; Cdc 25C; CDC25; CDC25C; Cell division cycle 25 homolog C; Cell division cycle 25C; Cell division cycle 25C protein; Dual specificity phosphatase Cdc25C; M phase inducer phosphatase 3; M-phase inducer phosphatase 3; Mitosis inducer CDC25; MPIP3; MPIP3_HUMAN; Phosphotyrosine phosphatase; PPP1R60; protein phosphatase 1, regulatory subunit 60] |
Gene, Accession # | [CDC25C], Gene ID: 995, NCBI: NP_001274511.1, UniProt: P30307 |
Catalog # | MBS9602601 |
Price | $235, $295, $370 |
Order / More Info | CDC25C Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |