Activating Transcription Factor 4 (ATF4) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Activating Transcription Factor 4 (ATF4) |
| Clone | monoclonal |
| Host Species | Mouse |
| Reactive Species | n/a |
| Isotype | IgG2a |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Immunoblot, Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody recognizes human and rat ATF4. ATF4 belongs to the large ATF/CREB family of transcription factors. These proteins bind DNA via their basic region and dimerize via their leucine zipper domain to form a variety of homo-and heterodimers that regulate gene transcription. Two alternative transcripts encoding the same protein have been described. ATF4 transcription factor is also known to play role in osteoblast differentiation. Terminal osteoblast differentiation, is significantly inhibited by the inactivation of JNK; JNK inactivation downregulates expression of ATF-4. |
| Immunogen | Immunogen: Fusion protein corresponding to aa 25-327 of human ATF4. This sequence is 86% identical in rat, 85% identical in mouse, and <50% identical in ATF5. |
| Other Names | [cyclic AMP-dependent transcription factor ATF-4; Cyclic AMP-dependent transcription factor ATF-4; cyclic AMP-dependent transcription factor ATF-4; activating transcription factor 4; Activating transcription factor 4; Cyclic AMP-responsive element-binding protein 2; CREB-2; cAMP-responsive element-binding protein 2; DNA-binding protein TAXREB67; Tax-responsive enhancer element-binding protein 67; TaxREB67], [ATF4; ATF4; CREB2; TXREB; CREB-2; TAXREB67; CREB2; TXREB; cAMP-dependent transcription factor ATF-4; CREB-2; cAMP-responsive element-binding protein 2; TaxREB67] |
| Gene, Accession # | [ATF4], Gene ID: 468, NCBI: NP_001666.2, UniProt: P18848 |
| Catalog # | MBS191367 |
| Price | $410 |
| Order / More Info | Activating Transcription Factor 4 (ATF4) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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