PSMA2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPSMA2
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, rat
Isotypen/a
Formatimmunogen affinity purified
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionRabbit IgG polyclonal antibody for Proteasome subunit alpha type-2(PSMA2) detection. Background: Proteasome subunit alpha type-2 is a protein that in humans is encoded by the PSMA2 gene. The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes
ImmunogenImmunogen: A synthetic peptide corresponding to a sequence in the middle region of human PSMA2 (82-123aa DYRVLVHRARKLAQQYYLVYQEPIPTAQLVQRVASVMQEYT Q), identical to the related mouse and rat sequences.
Other Names[HC3; MU; PMSA2; PSC2; PSC3; PSMA 2; PSMA2; P25787; Proteasome subunit alpha type-2; proteasome subunit alpha 2], [PSMA2; PSMA2; MU; HC3; PSC2; PMSA2; HC3; PSC3]
Gene, Accession #[PSMA2], Gene ID: 5683, NCBI: NP_002778.1, UniProt: P25787
Catalog #MBS178844
Price$280
Order / More InfoPSMA2 Antibody from MYBIOSOURCE INC.
Product Specific References1. Groll M, Ditzel L, Lowe J, Stock D, Bochtler M, Bartunik HD, Huber R (Apr 1997). Structure of 20S proteasome from yeast at 2.4 A resolution. Nature 386 (6624): 463-71.2. Tomko RJ, Hochstrasser M (2013). Molecular architecture and assembly of the eukaryotic proteasome. Annual Review of Biochemistry 82: 415-45.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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