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Antigenic Specificity | 5-LO (Phospho Ser272) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-5-LO (S272) Polyclonal Antibody detects endogenous levels of 5-LO protein only when phosphorylated at S272. ALOX5 encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The arachidonate 5-lipoxygenasen, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukot |
Immunogen | Immunogen: Synthesized peptide derived from human 5-LO around the phosphorylation site of S272 |
Other Names | [Rabbit 5-LO (phospho Ser272); ALOX5; LOG5; Arachidonate 5-lipoxygenase; 5-LO; 5-lipoxygenase] |
Gene, Accession # | [5-LO], Gene ID: 240, NCBI: NP_000689.1, UniProt: P09917 |
Catalog # | MBS9705033 |
Price | $130, $220, $325 |
Order / More Info | 5-LO (Phospho Ser272) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |