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Antigenic Specificity | mPD-1 |
Clone | [ABM5F42] |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2b kappa |
Format | Protein G purified |
Size | 0.025 mg, 0.1 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PDCD-1 (programmed cell death-1 protein), also designated CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. It is expressed on activated T-cells, B-cells, and myeloid cells. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. |
Immunogen | Immunogen Information: partial length recombinant protein (a.a 07-211) of mPD-1 was used as the immunogen for this antibody. |
Other Names | [Programmed cell death protein 1; Protein PD-1; CD279], [Pdcd1; Pdcd1; PD-1; Pdc1; Ly101; Pd1; Protein PD-1; mPD-1] |
Gene, Accession # | [PD-1], Gene ID: 18566, NCBI: Q02242.1, UniProt: Q02242 |
Catalog # | MBS668434 |
Price | $145, $290 |
Order / More Info | mPD-1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |