BAD Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityBAD
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunogen affinity purified
Size0.1 mg
Concentration1ug/ul
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC)
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DescriptionSpecificity: BAD (Ab-136) antibody detects endogenous levels of total BAD protein. This gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. [provided by RefSeq, Jul 2008]
ImmunogenImmunogen: This antiserum was produced against synthesized non-phosphopeptide derived from human BAD around the phosphorylation site of serine136 (S-R-SP-A-P).
Other Namesn/a
Gene, Accession #[BAD]
Catalog #MBS417201
Price$405
Order / More InfoBAD Antibody from MYBIOSOURCE INC.
Product Specific ReferencesWang XQ, et al. (2001). J Biol Chem.276 (48): 44504-44511.Lee YI, et al. (2001). J Biol Chem.276 (20): 16969-16977.Maiti D, et al. (2001). J Biol Chem.276 (1): 329-333.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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