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Antigenic Specificity | BAD |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | 1ug/ul |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: BAD (Ab-136) antibody detects endogenous levels of total BAD protein. This gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. [provided by RefSeq, Jul 2008] |
Immunogen | Immunogen: This antiserum was produced against synthesized non-phosphopeptide derived from human BAD around the phosphorylation site of serine136 (S-R-SP-A-P). |
Other Names | n/a |
Gene, Accession # | [BAD] |
Catalog # | MBS417201 |
Price | $405 |
Order / More Info | BAD Antibody from MYBIOSOURCE INC. |
Product Specific References | Wang XQ, et al. (2001). J Biol Chem.276 (48): 44504-44511.Lee YI, et al. (2001). J Biol Chem.276 (20): 16969-16977.Maiti D, et al. (2001). J Biol Chem.276 (1): 329-333. |