HSPD1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHSPD1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC)
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DescriptionIn both prokaryotic and eukaryotic cells the misfolding and aggregation of proteins during biogenesis and under conditions of cellular stress are prevented by molecular chaperones (1-3). HSP60 has primarily been known as a mitochondrial protein that is important for folding key proteins after import into the mitochondria (4). It is now clear that a significant amount of HSP60 is also present in the cytosol of many cells and that it is induced by stress, inflammatory and immune responses, autoantibodies correlated with Alzheimer's, coronary artery diseases, MS, and diabetes (5-8).
ImmunogenImmunogen: Recombinant protein of human HSPD1 Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Other Names[HSPD1; CPN60; GROEL; HLD4; HSP60; HSP65; HuCHA60; SPG13]
Gene, Accession #[HSPD1], Gene ID: 3329, NCBI: NP_002147.2, UniProt: P10809
Catalog #MBS8506005
Price$310
Order / More InfoHSPD1 Antibody from MYBIOSOURCE INC.
Product Specific References1. Hartl, F.U. (1996) Nature 381, 571-579. 2. Bukau, B. and Horwich, A.L. (1998) Cell 92, 351-366. 3. Hartl, F.U. and Hayer-Hartl, M. (2002) Science 295, 1852-1858. 4. Jindal, S. et al. (1989) Mol. Cell Biol. 9, 2279-2283. 5. Itoh, H. et al. (2002) Eur. J. Biochem. 269, 5931-5938. 6. Gupta, S. and Knowlton, A.A. J. Cell Mol. Med. 9, 51-58. 7. Deocaris, C.C. et al. (2006) Cell Stress Chaperones 11, 116-128. 8. Lai, H.C. et al. (2007) Am. J. Physiol. Endocrinol. Metab. 292, E292-E297.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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