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Antigenic Specificity | CYP17A1 (Center), 358-388 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: monkey) |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | Immunofluorescence (IF), ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This CYP17A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 358-388 amino acids from the Central region of human CYP17A1. CYP17A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in CYP17A1 gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alp |
Immunogen | n/a |
Other Names | [Steroid 17-alpha-hydroxylase/17,20 lyase; 17-alpha-hydroxyprogesterone aldolase; CYPXVII; Cytochrome P450 17A1; Cytochrome P450-C17; Cytochrome P450c17; Steroid 17-alpha-monooxygenase; CYP17A1; CYP17; S17AH] |
Gene, Accession # | [CYP17A1], Gene ID: 1586, NCBI: NP_000093.1, UniProt: P05093 |
Catalog # | MBS9213005 |
Price | $165, $370 |
Order / More Info | CYP17A1 (Center), 358-388 Antibody from MYBIOSOURCE INC. |
Product Specific References | Yuan,X., Cancer Epidemiol. Biomarkers Prev. 17 (12), 3621-3627 (2008) Nelson,D.R., Pharmacogenetics 14 (1), 1-18 (2004) Imai,T., Hum. Genet. 89 (1), 95-96 (1992) |