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Antigenic Specificity | Phospho-HSF1 (S326) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-HSF1 (S326) Antibody detects endogenous levels of total Phospho-HSF1 (S326). Heat shock transcription factors (HSF, also designated HSTF) 1 and 2 are involved in this regulation. HSF1 and HSF2 are upregulated by estrogen at both the mRNA and protein level. HSF1 is normally found as a monomer whose transcriptional activity is repressed by constitutive phosphorylation. Upon activation, HSF1 forms trimers, gains DNA binding activity and is translocated to the nucleus. HSF2 activity is associated with differentiation and development, and, like HSF1, binds DNA as a trimer. Both HSF1 and HSF2 are known to be induced by proteasome inhibitors of the ubiquitin pathway. |
Immunogen | Immunogen: A synthesized peptide derived from human Phospho-HSF1 (S326) |
Other Names | [HSF1; HSTF 1; HSTF1; Heat shock factor protein 1; Heat shock transcription factor 1], [HSF1; HSF1; HSTF1; HSTF 1] |
Gene, Accession # | [HSF1], Gene ID: 3297, NCBI: NP_005517.1, UniProt: Q00613 |
Catalog # | MBS477976 |
Price | $335 |
Order / More Info | Phospho-HSF1 (S326) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |