Mouse Wee1 (Center), 202-230 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Mouse Wee1 (Center), 202-230 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human (predicted reactivity: rat) |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.4 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This Mouse Wee1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 202-230 amino acids from the Central region of mouse Wee1. Wee1 may act as a negative regulator of entry into mitosis (G2 to M transition) by protecting the nucleus from cytoplasmically activated cyclin B1-complexed CDK1 before the onset of mitosis. Its activity increases during S and G2 phases and decreases at M phase when it is hyperphosphorylated. A correlated decrease in protein level occurs at M/G1 phase, probably due to its degradation. Specifically phosphorylates and inactivates cyclin B1-complexed CDK1 reaching a maximum during G2 phase and a minimum as cells enter M phase. Phosphorylation of cyclin B1-CDK1 occurs exclusively |
| Immunogen | n/a |
| Other Names | [Wee1-like protein kinase; Wee1A kinase; Wee1] |
| Gene, Accession # | [Wee1], Gene ID: 22390, NCBI: NP_033542.2, UniProt: P47810 |
| Catalog # | MBS9208291 |
| Price | $165, $370 |
| Order / More Info | Mouse Wee1 (Center), 202-230 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Muller, M., et al. J. Cell. Sci. 123 (PT 2), 286-294 (2010) : Kim, M.J., et al. Oncol. Rep. 19(5):1323-1329(2008) Tanaka, Y., et al. Biochem. Biophys. Res. Commun. 352(1):21-28(2007) Tominaga, Y., et al. Int. J. Biol. Sci. 2(4):161-170(2006) Park, C.E., et al. Cells Tissues Organs (Print) 177(4):221-228(2004) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
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