Edit |   |
---|---|
Antigenic Specificity | MBNL3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mediates pre-mRNA alternative splicing regulation. Acts either as activator or repressor of splicing on specific pre-mRNA targets. Inhibits cardiac troponin-T (TNNT2) pre-mRNA exon inclusion but induces insulin receptor (IR) pre-mRNA exon inclusion in muscle. Antagonizes the alternative splicing activity pattern of CELF proteins. May play a role in myotonic dystrophy pathophysiology (DM). Could inhibit terminal muscle differentiation, acting at approximately the time of myogenin induction. |
Immunogen | Immunogen: Recombinant Human Muscleblind-like protein 3 protein (116-211AA) |
Other Names | [Muscleblind-like protein 3; Cys3His CCG1-required protein; Muscleblind-like X-linked protein; Protein HCHCR; MBNL3; CHCR; MBLX39; MBXL] |
Gene, Accession # | [MBNL3], Gene ID: 55796, NCBI: NP_001164172.1, UniProt: Q9NUK0 |
Catalog # | MBS7109500 |
Price | $160, $235 |
Order / More Info | MBNL3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |