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Antigenic Specificity | DC-SIGNR [16E7] |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein A purified |
Size | 0.2 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Human CD299, which is an oligomeric type II transmembrane protein with a C-type lectin extracellular domain, the expression of which is restricted to immature DC, macrophages in the lung, and endothelial cells in the liver. It binds ICAM-3 and ICAM-7 to mediate the interaction of DC with T lymphocytes and endothelial cells in the initial stages of immune response and in the migratory behavior of DC. CD299 also binds the gp120 protein of HIV and the E2 envelope protein of HCV, thereby playing a role in viral infection. Recombinant monoclonal antibody to DC-SIGNR. Manufactured using a Recombinant Platform with variable regions (i.e. specificity) from the hybridoma 16E7. This chimeric rabbit antibody was made using the variable do |
Immunogen | Immunogen: CD299 Chimeric Use Statement: This chimeric rabbit antibody was made using the variable domain sequences of the original murine IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
Other Names | [CD299; C-type lectin domain family 4 member M; CD209 antigen-like protein 1; DC-SIGN-related protein; CLEC4M; Dendritic cell-specific ICAM-3-grabbing non-integrin 2; DC-SIGN2; Liver/lymph node-specific ICAM-3-grabbing non-integrin; L-SIGN], [CLEC4M; CLEC4M; CD299; LSIGN; CD209L; L-SIGN; DCSIGNR; HP10347; DC-SIGN2; DC-SIGNR; CD209L; CD209L1; CD299; DC-SIGNR; DC-SIGN2; L-SIGN] |
Gene, Accession # | [DC-SIGNR], Gene ID: 10332, UniProt: Q9H2X3 |
Catalog # | MBS488088 |
Price | $425 |
Order / More Info | DC-SIGNR [16E7] Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |