HSP90 beta Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | HSP90 beta |
| Clone | [Hyb-K3701] |
| Host Species | Mouse |
| Reactive Species | human, mouse |
| Isotype | IgM |
| Format | APC-Cy7 conjugate |
| Size | 0.1 mg |
| Concentration | 1 mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Detects 90 kDa. This is a beta specific product, does not cross-react with alpha isoforms. HSP90 is an abundantly and ubiquitously expressed heat shock protein. It is understood to exist in two principal forms alpha and beta, which share 85% sequence amino acid homology. The two isoforms of HSP90 are expressed in the cytosolic compartment (1). Despite the similarities, HSP90alpha exists predominantly as a homodimer while HSP90beta exists mainly as a monomer (2). From a functional perspective, HSP90 participates in the folding, assembly, maturation, and stabilization of specific proteins as an integral component of a chaperone complex (3-6). Furthermore, HSP90 is highly conserved between species; having 60% and 78% amino acid similarity betw |
| Immunogen | Immunogen: Recombinant human HSP90beta; Specificity mapped to amino acids 185-335 |
| Other Names | [Mouse Human HSP90 beta IgM; HSP90 beta : APC/Cy7; HSP84; HSP90B; HSPC2; HSPCB; D6S182. FLJ26984] |
| Gene, Accession # | [HSP90B], Gene ID: 3326, NCBI: NP_001258898.1, UniProt: P08238 |
| Catalog # | MBS8002260 |
| Price | $525 |
| Order / More Info | HSP90 beta Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Nemoto, T. et al. (1997) J.Biol Chem. 272: 26179-26187. 2. Minami Y, et al. (1991), J.Biol Chem. 266: 10099-10103. 3. Arlander SJH, et al. (2003) J Biol Chem 278: 52572-52577. 4. Pearl H, et al. (2001) Adv Protein Chem 59: 157-186. 5. Neckers L, et al. (2002) Trends Mol Med 8: S55-S61. 6. Pratt W, Toft D. (2003) Exp Biol Med 228: 111-133. 7. Pratt W, Toft D. (1997) Endocr Rev 18: 306-360. 8. Pratt WB. (1998) Proc Soc Exptl Biol Med 217: 420-434. 9. Whitesell L, et al. (1994) Proc Natl Acad Sci USA 91: 8324-8328. 10. Kishimoto J, et al. (2005). Cell Stress and Chaperones. 10 (4): 296-311. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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