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Antigenic Specificity | APAF1 |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg, 0.1 mg |
Concentration | n/a |
Applications | Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis. |
Immunogen | Immunogen: A synthesized peptide derived from human APAF1. Subcellular Localization: Cytoplasm. Tissue Specificity: Ubiquitous. Highest levels of expression in adult spleen and peripheral blood leukocytes, and in fetal brain, kidney and lung. Isoform 1 is expressed in heart, kidney and liver. |
Other Names | [Apoptotic protease-activating factor 1; APAF-1; APAF1; KIAA0413], [APAF1; APAF1; CED4; APAF-1; KIAA0413; APAF-1] |
Gene, Accession # | [APAF1], Gene ID: 317, NCBI: NP_001151.1, UniProt: O14727 |
Catalog # | MBS179483 |
Price | $160, $340, $340 |
Order / More Info | APAF1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |