APAF1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityAPAF1
Clonemonoclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formataffinity purified
Size0.03 mg, 0.1 mg, 0.1 mg
Concentrationn/a
ApplicationsImmunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Western Blot (WB)
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DescriptionOligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis.
ImmunogenImmunogen: A synthesized peptide derived from human APAF1. Subcellular Localization: Cytoplasm. Tissue Specificity: Ubiquitous. Highest levels of expression in adult spleen and peripheral blood leukocytes, and in fetal brain, kidney and lung. Isoform 1 is expressed in heart, kidney and liver.
Other Names[Apoptotic protease-activating factor 1; APAF-1; APAF1; KIAA0413], [APAF1; APAF1; CED4; APAF-1; KIAA0413; APAF-1]
Gene, Accession #[APAF1], Gene ID: 317, NCBI: NP_001151.1, UniProt: O14727
Catalog #MBS179483
Price$160, $340, $340
Order / More InfoAPAF1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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