BLK (B lymphoid tyrosine kinase) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityBLK (B lymphoid tyrosine kinase)
Clonemonoclonal
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
Formatascites
Size0.1 mL
Concentration1ug/ul
ApplicationsELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
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DescriptionBLK (B lymphoid tyrosine kinase), with 505-amino acid protein (about 56KDa), belongs to the Src non-receptor tyrosine kinases family.Different subcellular localizations of Src-family kinases may be important for the regulation of specific cellular processes such as mitogenesis, cytoskeletal organization, and membrane trafficking.Blk is expressed exclusively by B lymphocytes and it is thought to function in a signal transductory pathway specific to this lineage. B lymphoid expression of an active Blk mutant caused proliferation of B progenitor cells and enhanced responsiveness of these cells to interleukin 7. Thus, sustained activation of Blk induces responses normally associated with the pre-BCR.
ImmunogenImmunogen: Ni-NTA purified truncated recombinant BLK expressed in E Coli strain BL21 (DE3)
Other Names[B lymphoid tyrosine kinase; Tyrosine-protein kinase Blk; tyrosine-protein kinase Blk; BLK proto-oncogene, Src family tyrosine kinase; B lymphocyte kinase; p55-Blk], [BLK; BLK; MODY11]
Gene, Accession #[BLK], Gene ID: 640, NCBI: AAH32413.1
Catalog #MBS418366
Price$445
Order / More InfoBLK (B lymphoid tyrosine kinase) Antibody from MYBIOSOURCE INC.
Product Specific References1.Theresa Tretter, Ashley E. Ross, Dominic I. Dordai J. Exp. Med., Dec 2003; 198: 1863.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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