Edit |   |
---|---|
Antigenic Specificity | BRSK1 (Center), 355-384 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse (predicted reactivity: rat) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This BRSK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 355-384 amino acids from the Central region of human BRSK1. Required for the polarization of forebrain neurons which endows axons and dendrites with distinct properties, possibly by locally regulating phosphorylation of microtubule-associated proteins (By similarity). May be involved in the regulation of G2/M arrest in response to UV-or methyl methane sulfonate (MMS)-induced, but not IR-induced, DNA damage. Phosphorylates WEE1 and CDC25B in vitro and CDC25C in vitro and in vivo. |
Immunogen | n/a |
Other Names | [Serine/threonine-protein kinase BRSK1; Brain-selective kinase 1; Brain-specific serine/threonine-protein kinase 1; BR serine/threonine-protein kinase 1; Serine/threonine-protein kinase SAD-B; Synapses of Amphids Defective homolog 1; SAD1 homolog; hSAD1; BRSK1; KIAA1811; SAD1; SADB] |
Gene, Accession # | [BRSK1], Gene ID: 84446, NCBI: NP_115806.1, UniProt: Q8TDC3 |
Catalog # | MBS9201409 |
Price | $165, $370 |
Order / More Info | BRSK1 (Center), 355-384 Antibody from MYBIOSOURCE INC. |
Product Specific References | Alvarado-Kristensson, M., et al. Nat. Cell Biol. 11(9):1081-1092(2009) He, C., et al. Nat. Genet. (2009) In press : Stolk, L., et al. Nat. Genet. (2009) In press : Fogarty, S., et al. J. Biol. Chem. 284(1):77-84(2009) Bright, N.J., et al. J. Biol. Chem. 283(22):14946-14954(2008) |