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Antigenic Specificity | TBP |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 1.1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total TBP protein. This gene encodes TBP, the TATA-binding protein.A distinctive feature of TBP is a long string of glutamines in the N-terminus. This region of the protein modulates the DNA binding activity of the C terminus, and modulation of DNA binding affects the rate of transcription complex formation and initiation of transcription. The number of CAG repeats encoding the polyglutamine tract is usually 32-39, and expansion of the number of repeats increases the length of the polyglutamine string and is associated with spinocerebellar ataxia 17, a neurodegenerative disorder classified as a polyglutamine disease. |
Immunogen | Immunogen: Full length fusion protein of human TBP |
Other Names | [HDL4; GTF2D; SCA17; TFIID; GTF2D1] |
Gene, Accession # | [TBP], Gene ID: 6908, NCBI: NP_001165556.1, UniProt: P20226 |
Catalog # | MBS9416125 |
Price | $255 |
Order / More Info | TBP Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |