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Antigenic Specificity | PTGES3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2) (PubMed:10922363). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes (PubMed:11274138, PubMed:12077419). Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 to the HSP90 pathway (PubMed:24711448). |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PTGES3 (NP 006592.3). |
Other Names | [P23; TEBP; cPGES] |
Gene, Accession # | [PTGES3], Gene ID: 10728, NCBI: NP_006592.3, UniProt: Q15185 |
Catalog # | MBS8545504 |
Price | $280 |
Order / More Info | PTGES3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |