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Antigenic Specificity | PVRL4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: PVRL4 antibody detects endogenous levels of total PVRL4. Function: Seems to be involved in cell adhesion through trans-homophilic and-heterophilic interactions, the latter including specifically interactions with NECTIN1. Does not act as receptor for alpha-herpesvirus entry into cells.Subunit Structure: Self-associates. Interacts via its Ig-like V-type domain with NECTIN1 Ig-like V-type domain. Interacts via its C-terminus with AFDN.Post-translational Modifications: The soluble form is produced by proteolytic cleavage at the cell surface (shedding), probably by ADAM17/TACE.Similarity: Belongs to the nectin family. |
Immunogen | Immunogen: A synthesized peptide Subcellular Location: Cell Membrane. Cell Junction > Adherens Junction. Colocalizes with MLLT4 at cadherin-based adherens junctions and Secreted. The secreted form is found in breast tumor patients. Tissue Specificity: Predominantly expressed in placenta. Not detected in normal breast epithelium but expressed in breast carcinoma. |
Other Names | [DKFZp686K05193; EDSS1; Ig superfamily receptor LNIR; Nectin 4; Nectin-4; poliovirus receptor-related 4; Processed poliovirus receptor-related protein 4; PRR4; pvrl4; PVRL4_HUMAN] |
Gene, Accession # | [PVRL4], Gene ID: 81607, NCBI: NP_112178.2, UniProt: Q96NY8 |
Catalog # | MBS9605756 |
Price | $240, $280 |
Order / More Info | PVRL4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |