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Antigenic Specificity | Ku70 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Ku70 Antibody detects endogenous levels of total Ku70. It works in the 3'-5' direction. Binding to DNA may be mediated by XRCC6. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The XRCC5/6 dimer acts as regulatory subunit of the DNA-dependent protein kinase complex DNA-PK by increasing the affinity of the catalytic subunit PRKDC to DNA by 100-fold. The XRCC5/6 dimer is probably involved in stabilizing broken DNA ends and bringing them together. |
Immunogen | Immunogen: A synthesized peptide derived from human Ku70 |
Other Names | [CTC75; CTCBF; DNA repair protein XRCC6; G22P1; Ku 70; Ku autoantigen 70kDa; Ku autoantigen; 70kDa; Ku p70; Ku70; Kup70; TLAA; XRCC6] |
Gene, Accession # | [Ku70], Gene ID: 2547, NCBI: NP_001275905.1, UniProt: P12956 |
Catalog # | MBS4750845 |
Price | $335 |
Order / More Info | Ku70 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |