GP6 (C-term), 309-337 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityGP6 (C-term), 309-337
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpeptide affinity purified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 0.5
ApplicationsWestern Blot (WB), ELISA (EIA), Flow Cytometry (FC/FACS)
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DescriptionThis GP6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 309-337 amino acids from the C-terminal region of human GP6. Glycoprotein VI (GP6) is a 58-kD platelet membraneglycoprotein that plays a crucial role in the collagen-inducedactivation and aggregation of platelets. Upon injury to the vesselwall and subsequent damage to the endothelial lining, exposure ofthe subendothelial matrix to blood flow results in deposition ofplatelets. Collagen fibers are the most thrombogenic macromolecularcomponents of the extracellular matrix, with collagen types I, III,and VI being the major forms found in blood vessels. Plateletinteraction with collagen occurs as a 2-step procedur
Immunogenn/a
Other Names[Platelet glycoprotein VI; GPVI; Glycoprotein 6; GP6]
Gene, Accession #[GP6], Gene ID: 51206, NCBI: NP_001242946.1, UniProt: Q9HCN6
Catalog #MBS9211313
Price$165, $370
Order / More InfoGP6 (C-term), 309-337 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesPolgar, J., et al. J. Biol. Chem. 272(21):13576-13583(1997) Asselin, J., et al. Blood 89(4):1235-1242(1997) Huang, M.M., et al. Proc. Natl. Acad. Sci. U.S.A. 88(17):7844-7848(1991) Moroi, M., et al. J. Clin. Invest. 84(5):1440-1445(1989)
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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