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Antigenic Specificity | IL4R |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | IL4R is a human gene that encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE antibody production in B cells. The IL4R gene is localized to 16p12.1-p11.2 by in situ hybridization and Southern blot analysis of DNA from a panel of mouse-human somatic cell lines. IL4 plays a major role in immunoglobulin E (IgE) production. Its signal is conferred to effector cells through binding to the alpha chain of the IL4 receptor. IL4 interacts with IL4R with high affinity, leading to dimerization with either the common gamma chain,a component of receptors for a number of cytokines, to create a type I receptor, or with IL13RA1 to form a type II receptor. |
Immunogen | Immunogen: IL4R antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence in the middle region of human IL4R as the immunogen |
Other Names | [Affinity Purified Rabbit IL4R; IL4R; IL4R; ILR-4; ILR-4; IL4R; ILR 4; Interleukin 4 Receptor; ILR 4] |
Gene, Accession # | [IL4R] |
Catalog # | MBS5312919 |
Price | $345 |
Order / More Info | IL4R Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |