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Antigenic Specificity | MAGEC1 (C-term), 849-880 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This MAGEC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 849-880 amino acids from the C-terminal region of human MAGEC1. MAGEC1 is a member of the melanoma antigen gene (MAGE) family. The proteins of this family are tumor-specific antigens that can be recognized by autologous cytolytic T lymphocytes. This protein contains a large number of unique short repetitive sequences in front of the MAGE-homologous sequence, thus is about 800 residues longer than the other MAGE proteins. This gene is expressed in a significant proportion of tumors of various histological types, whereas it is silent in normal tissues, except testis. The function of this gene is unknown. |
Immunogen | n/a |
Other Names | [Melanoma-associated antigen C1; Cancer/testis antigen 71; CT71; MAGE-C1 antigen; MAGEC1] |
Gene, Accession # | [MAGEC1], Gene ID: 9947, NCBI: NP_005453.2, UniProt: O60732 |
Catalog # | MBS9207108 |
Price | $165, $370 |
Order / More Info | MAGEC1 (C-term), 849-880 Antibody from MYBIOSOURCE INC. |
Product Specific References | Jungbluth, A.A., et al., Int. J. Cancer 99(6):839-845 (2002). Chen, Y.T., et al., Proc. Natl. Acad. Sci. U.S.A. 95(12):6919-6923 (1998). Lucas, S., et al., Cancer Res. 58(4):743-752 (1998). Lim, S.H., et al., Eur. J. Haematol. 67 (5-6), 332-334 (2001). |