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Antigenic Specificity | ASIC1 |
Clone | [S271-44] |
Host Species | Mouse |
Reactive Species | mouse, rat |
Isotype | IgG1 |
Format | APC-Cy7 conjugate |
Size | 0.1 mg |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Detects ~60 kDa. Acid sensing ion channel ASIC1, also designated ACCN2, BNAC2 and ASIC1a, is present in brain as a 4.3-kb transcript with localization to rat dorsal root ganglia. Insitu hybridization of rat brain suggests that ASIC1 is most abundant in the main olfactory bulb, cerebral cortex, hippocampal formation, habenula, basolateral amygdaloid nuclei and cerebellum. ASIC1 and H+-gated currents may contribute to the development of fear and anxiety. |
Immunogen | Immunogen: Fusion protein amino acids 460-526 (Cytoplasmic C-terminus) of mouse ASIC1 |
Other Names | [Mouse Mouse ASIC1 IgG1; ASIC1 : APC/Cy7; ACCN2; Acid-sensing (proton-gated) ion channel; Acid-sensing ion channel 1; Amiloride-sensitive cation channel 2 neuronal; BNAC2; Brain sodium channel 2] |
Gene, Accession # | [ASIC1], Gene ID: 11419, NCBI: NP_033727.1, UniProt: Q6NXK8 |
Catalog # | MBS8003256 |
Price | $510 |
Order / More Info | ASIC1 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Garcia-Anoveros J., Derfler B., Neville-Golden J., Hyman B.T. and Corey D.P. (1997) Proc. Natl. Acad. Sci. USA 94: 1459-1464. 2. Waldmann R., Champigny G., Bassilana F., Heurteaux C. and Lazdunski M. (1997) Nature. 386: 173-177. 3. Grunder S., Geisler H.S., Rainier S. and Fink J.K. (2001) Eur. J. Hum. Genet. 9:672-676. 4. Chen C.C., Zimmer A., Sun W.H., Hall J., Brownstein M.J. and Zimmer A. (2002) Proc. Natl. Acad. Sci. USA 99: 8992-8997. 5. Wemmie J.A., et al. (2004) Proc. Natl. Acad. Sci. USA 101: 3621-3626. |