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Antigenic Specificity | p47 phox |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | humanpredicted: porcine, zebrafish, bovine, sheep, dog, chicken |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Peptide ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: p47 phox Antibody detects endogenous levels of p47 phox. Description: NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production).Post Translational Modifications: Phosphorylated by PRKCD; phosphorylation induces activation of NCF1 and NADPH oxidase activity.Subunit Structure: Component of an NADPH oxidase complex composed of a heterodimer formed by the membrane proteins CYBA and CYBB and the cytosolic subunits NCF1, NCF2 and NCF4. Interacts (via C-terminus) with NCF2 (via the C-terminal SH3 domain). Interacts with NCF4. Interacts with CYBB. Interacts (via the second SH3 domain) with CYBA. Interacts with NOXA1. Interacts with ADAM |
Immunogen | Immunogen: A synthesized peptide derived from human p47 phox. Tissue Specificity: Detected in peripheral blood monocytes and neutrophils (at protein level). |
Other Names | [47 kDa autosomal chronic granulomatous disease protein; 47 kDa neutrophil oxidase factor; NADPH oxidase organizer 2; NCF 47K; NCF-1; NCF-47K; Ncf1; NCF1_HUMAN; Neutrophil cytosol factor 1; Neutrophil cytosolic factor 1; neutrophil cytosolic factor 1, (chronic granulomatous disease, autosomal 1); Neutrophil NADPH oxidase factor 1; Nox organizer 2; Nox organizing protein 2; Nox-organizing protein 2; NOXO2; p47 phox; p47-phox; SH3 and PX domain containing protein 1A; SH3 and PX domain-containing protein 1A; SH3PXD1A] |
Gene, Accession # | [p47phox], Gene ID: 653361, NCBI: NP_000256.3, UniProt: P14598 |
Catalog # | MBS9611015 |
Price | $225, $280, $340 |
Order / More Info | p47 phox Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |