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Antigenic Specificity | HK1 |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG1 |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: HK1 antibody detects endogenous levels of total HK1. Description: Hexokinases phosphorylate glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in five transcript variants which encode different isoforms, some of which are tissue-specific. Each isoform has a distinct N-terminus; the remainder of the protein is identical among all the isoforms. A sixth transcript variant has been described, but due to the presence of several stop codons, it is not thou |
Immunogen | Immunogen: Purified recombinant fragment of human HK1 expressed in E. Coli Subcellular Location: Mitochondrion Outer Membrane. Its hydrophobic N-terminal sequence may be involved in membrane binding. Tissue Specificity: Isoform 2 is erythrocyte specific. Isoform 3 and isoform 4 are testis-specific. |
Other Names | [Brain form hexokinase; Hexokinase 1; Hexokinase type I; HK I; HK1 ta; HK1 tb; HK1 tc; HKI; HXK1] |
Gene, Accession # | [HK1], Gene ID: 3098, NCBI: NP_000179.2, UniProt: P19367 |
Catalog # | MBS9602396 |
Price | $235, $295, $370 |
Order / More Info | HK1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |