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Antigenic Specificity | TORC1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for CREB-regulated transcription coactivator 1(CRTC1) detection. Tested with WB in Human, Mouse, Rat. Background: CRTC1(CREB-Regulated Transcription Coactivator 1), also known as MECT1, TORC1 or KIAA0616, is a protein that in humans is encoded by the CRTC1 gene. By sequence analysis, Tonon et al.(2003) mapped the CRTC1 gene to chromosome 19p13. Kovacs et al.(2007) found that Torc1 was expressed in adult mouse brain and cultured neurons, and that it translocated to the nucleus upon concomitant activation of calcium and cAMP signaling pathways. Mair et al.(2011) demonstrated that CRTC1 is a direct AMPK target, and interacts with the CREB homolog-1(CRH1) transcription factor in vivo. The prolongevity |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human TORC1 (506-521aa EQQMAARQANALSHQL), different from the related rat and mouse sequences by two amino acids. |
Other Names | [CREB-regulated transcription coactivator 1; CREB regulated transcription coactivator 1; KIAA0616; CREB regulated transcription coactivator 1; CREB-regulated transcription coactivator 1; CRTC1; CRTC1_HUMAN; FLJ14027; MECT 1; Mucoepidermoid carcinoma translocated 1; Mucoepidermoid carcinoma translocated protein 1; TORC-1; TORC1; Transducer of CREB protein 1; Transducer of regulated cAMP response element binding protein 1; Transducer of regulated cAMP response element-binding protein(CREB) 1; Transducer of regulated cAMP response element-binding protein 1; WAMTP1], [CRTC1; CRTC1; MECT1; TORC1; TORC-1; WAMTP1; TORC-1; Transducer of CREB protein 1] |
Gene, Accession # | [CRTC1], Gene ID: 23373, NCBI: Q6UUV9.2, UniProt: Q6UUV9 |
Catalog # | MBS176102 |
Price | $280 |
Order / More Info | TORC1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |