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Antigenic Specificity | HNRNPK |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), RIP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Heterogeneous nuclear ribonucleoprotein K (hnRNP K) belongs to a family of RNA binding multiprotein complexes (hnRNP proteins) that facilitate pre-mRNA processing and transport of mRNA from the nucleus to cytoplasm (1-3). hnRNP K contains three unique structural motifs termed KH domains that bind poly(C) DNA and RNA sequences (4,5). Intricate architecture enables hnRNP K to facilitate mRNA biosynthesis (6), transcriptional regulation (7), and signal transduction. Research studies have shown that cytoplasmic hnRNP K expression is increased in oral squamous cell carcinoma and pancreatic cancer, and may be a potential prognostic factor (8,9). hnRNP K coordinates with p53 to regulate its target gene transcription in response to DNA damage. Prot |
Immunogen | Immunogen: Recombinant Protein |
Other Names | [CSBP; FLJ41122; HNRPK; TUNP], [HNRNPK; HNRNPK; CSBP; TUNP; HNRPK; HNRPK; hnRNP K; TUNP] |
Gene, Accession # | [HNRNPK], Gene ID: 3190, NCBI: P61978.1, UniProt: P61978 |
Catalog # | MBS126331 |
Price | $200, $275, $430 |
Order / More Info | HNRNPK Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |