Edit |   |
---|---|
Antigenic Specificity | C2CD3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Component of the centrioles that acts as a positive regulator of centriole elongation (PubMed: 24997988). Promotes assembly of centriolar distal appendage, a structure at the distal end of the mother centriole that acts as an anchor of the cilium, and is required for recruitment of centriolar distal appendages proteins CEP83, SCLT1, CEP89, FBF1 and CEP164. Not required for centriolar satellite integrity or RAB8 activation. Required for primary cilium formation (PubMed: 23769972). Required for sonic hedgehog/SHH signaling and for proteolytic processing of GLI3. |
Immunogen | Immunogen: Recombinant human C2 domain-containing protein 3 protein (2079-2265AA) |
Other Names | [C2 domain-containing protein 3; C2CD3] |
Gene, Accession # | [C2CD3], Gene ID: 26005, NCBI: NP_001273506.1, UniProt: Q4AC94 |
Catalog # | MBS7050353 |
Price | $160, $235 |
Order / More Info | C2CD3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |