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Antigenic Specificity | Mouse TLR2 (C-term), 720-749 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This Mouse TLR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 720-749 amino acids from the C-terminal region of mouse TLR2. TLR2 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. TLR2 is expressed most abundantly in peripheral blood leukocytes, and mediat |
Immunogen | n/a |
Other Names | [Toll-like receptor 2; CD282; Tlr2] |
Gene, Accession # | [Tlr2], Gene ID: 24088, NCBI: NP_036035.3, UniProt: Q9QUN7 |
Catalog # | MBS9213149 |
Price | $165, $370 |
Order / More Info | Mouse TLR2 (C-term), 720-749 Antibody from MYBIOSOURCE INC. |
Product Specific References | Okazaki, Y., et al., Nature 420(6915):563-573 (2002). Lin, Y., et al., J. Biol. Chem. 275(32):24255-24263 (2000). Matsuguchi, T., et al., Blood 95(4):1378-1385 (2000). Heine, H., et al., J. Immunol. 162(12):6971-6975 (1999). Underhill, D.M., et al., Nature 401(6755):811-815 (1999). |