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Antigenic Specificity | CD40 - N-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | guinea pig, horse, human, rabbit |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against CD40. It was validated on Western Blot using a cell lysate as a positive control.Target Description: CD40 is the receptor for TNFSF5/CD40LG. Defects in CD40 are the cause of hyper-IgM immunodeficiency type 3 (HIGM3).The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CD40 |
Other Names | [tumor necrosis factor receptor superfamily member 5 isoform 1; Tumor necrosis factor receptor superfamily member 5; tumor necrosis factor receptor superfamily member 5; CD40 molecule; B-cell surface antigen CD40; Bp50; CD40L receptor; CDw40] |
Gene, Accession # | [CD40], Gene ID: 958, NCBI: NP_690593, UniProt: P25942 |
Catalog # | MBS3206115 |
Price | $335 |
Order / More Info | CD40 - N-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |