PIAS3 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPIAS3
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatantigen affinity purified
Size0.1 mL
Concentration1.0 mg/ml
ApplicationsImmunohistochemistry (IHC)
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DescriptionThe antibody detects endogenous level of total PIAS3 polyclonal antibody. Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor.Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway and the steroid hormone signaling pathway.Involved in regulating STAT3 signaling via inhibiting STAT3 DNA-binding and suppressing cell growth. Enhances the sumoylation of MTA1 and may participate in its paralog-selective sumoylation.
ImmunogenImmunogen: Recombinant Human E3 SUMO-protein ligase PIAS3 protein (399-628aa)
Other Names[Protein inhibitor of activated STAT protein 3; PIAS3]
Gene, Accession #[PIAS3], Gene ID: 10401, NCBI: NP_006090.2, UniProt: Q9Y6X2
Catalog #MBS9416052
Price$320
Order / More InfoPIAS3 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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