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Antigenic Specificity | Grp94 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat, bovine |
Isotype | n/a |
Format | Protein A purified |
Size | 0.2 mg |
Concentration | n/a |
Applications | Immunocytochemistry (ICC), Immunohistochemistry (IHC) Paraffin, Immunoprecipitation (IP), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes human, mouse, rat and bovine Grp94. Detects a band of ~94kDa by Western blot. Grp94 (Glucose-regulated protein 94) is an abundant resident endoplasmic reticulum (ER) lumenal stress protein, which together with cytosolic Hsp90 belongs to the Hsp90 family of molecular chaperones. Grp94 expression is upregulated by stress conditions such as glucose starvation and heat shock, which promote protein misfolding or unfolding. In addition to a homeostatic role in protein folding and assembly, Grp94 can function in the intracellular trafficking of peptides from the extracellular space to the MHC class I antigen processing pathway of antigen presentation cells. |
Immunogen | Immunogen: Synthetic peptide corresponding to the sequence near the C-terminus of mouse Grp94. |
Other Names | [Endoplasmin; Tra1; Hsp90B1; Gp96; Grp94, pAb], [Hsp90b1; Hsp90b1; TA-3; Tra1; gp96; ERp99; GRP94; Targ2; Tra-1; endoplasmin; Grp94; Tra-1; Tra1; GRP-94; ERp99] |
Gene, Accession # | [Grp94], Gene ID: 22027, NCBI: NP_035761, UniProt: P08113 |
Catalog # | MBS565744 |
Price | $460 |
Order / More Info | Grp94 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |