Phospho-ATF1 (Ser198) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-ATF1 (Ser198)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, ratpredicted: porcine, zebrafish, bovine, horse, sheep, rabbit, dog, chicken, Xenopus
Isotypen/a
Formatpeptide affinity purified
Size0.05 mL, 0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Peptide ELISA (EIA)
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DescriptionSpecificity: Phospho-ATF1 (Ser198) Antibody detects endogenous levels of ATF1 only when phosphorylated at Ser198. Description: This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Binds to the Tax-responsive element (TRE) of HTLV-I. Mediates PKA-induced stimulation of CRE-reporter genes. Represses the expression of FTH1 and other antioxidant detoxification genes. Triggers cell proliferation and transformation.Post Translational Modifications: Phosphorylated at Ser-198 by HIPK2 in response to genotoxic stress. This phosphorylation promotes transcription repression of FTH1 and other antioxidant detoxification genes. The CDK3-mediated phosphoryla
ImmunogenImmunogen: A synthesized peptide derived from human ATF1 around the phosphorylation site of Ser198.
Other Names[Activating transcription factor 1; ATF 1; atf1; ATF1 EWS fusion gene; ATF1 FUS fusion gene; ATF1_HUMAN; cAMP dependent transcription factor 1; cAMP-dependent transcription factor ATF-1; Cyclic AMP dependent transcription factor ATF 1; Cyclic AMP dependent transcription factor ATF1; Cyclic AMP-dependent transcription factor ATF-1; EWS AFT1; FUS ATF 1; FUS/ATF 1; Protein TREB36; RNA binding protein activating transcription factor 1 fusion protein; TREB 36; TREB36; TREB36 protein]
Gene, Accession #[ATF1], Gene ID: 466, NCBI: NP_005162.1, UniProt: P18846
Catalog #MBS9610614
Price$225, $280, $340
Order / More InfoPhospho-ATF1 (Ser198) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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