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Antigenic Specificity | DDX42 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | fluorescein (FITC) conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ATP-dependent RNA helicase. Binds to partially double-stranded RNAs (dsRNAs) in order to unwind RNA secondary structures. Unwinding is promoted in the presence of single-strand binding proteins. Mediates also RNA duplex formation thereby displacing the single-strand RNA binding protein. ATP and ADP modulate its activity: ATP binding and hydrolysis by DDX42 triggers RNA strand separation, whereas the ADP-bound form of the protein triggers annealing of complementary RNA strands. Involved in the survival of cells by interacting with TP53BP2 and thereby counteracting the apoptosis-stimulating activity of TP53BP2. Relocalizes TP53BP2 to the cytoplasm. |
Immunogen | Immunogen: Recombinant human ATP-dependent RNA helicase DDX42 protein Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-132256 / sc-132257 |
Other Names | [ATP-dependent RNA helicase DDX42 (EC:3.6.4.13); DDX42; DEAD box protein 42; RNA helicase-like protein; RHELP; RNA helicase-related protein; RNAHP; SF3b DEAD box protein; Splicing factor 3B-associated 125 kDa protein; SF3b125], [DDX42; DDX42; RHELP; RNAHP; SF3B8; DDX42P; SF3b125; RHELP; RNAHP; SF3b125] |
Gene, Accession # | [DDX42], Gene ID: 11325, NCBI: NP_031398.2, UniProt: Q86XP3 |
Catalog # | MBS968814 |
Price | $160, $235 |
Order / More Info | DDX42 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |