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Antigenic Specificity | SPHK2 (Phospho Thr614) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-SphK2 (T614) Polyclonal Antibody detects endogenous levels of SphK2 protein only when phosphorylated at T614. SPHK2 (sphingosine kinase 2) encodes one of two sphingosine kinase isozymes that catalyze the phosphorylation of sphingosine into sphingosine 1-phosphate. Sphingosine 1-phosphate mediates many cellular processes including migration, proliferation and apoptosis, and also plays a role in several types of cancer by promoting angiogenesis and tumorigenesis. The encoded protein may play a role in breast cancer proliferation and chemoresistance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for SPHK2. |
Immunogen | Immunogen: Synthesized peptide derived from human SphK2 around the phosphorylation site of T614 |
Other Names | [Rabbit SphK2 (phospho Thr614); SPHK2; Sphingosine kinase 2; SK 2; SPK 2] |
Gene, Accession # | [SPHK2], Gene ID: 56848, NCBI: NP_001191088.1, UniProt: Q9NRA0 |
Catalog # | MBS9706488 |
Price | $130, $220, $325 |
Order / More Info | SPHK2 (Phospho Thr614) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |