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Antigenic Specificity | PRRX1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: PRRX1 antibody is human, mouse and rat reactive. At least two isoforms of PRRX1 are known to exist; this antibody will detect both isoforms. The paired related homeobox protein 1 (PRRX1) is a paired-type DNA-binding homeodomain that plays an important role as a key switch for neural cell lineage determination and is essential for development (1,2). PRRX1 is expressed in a number of undifferentiated mesenchymal cells in mouse embryos and adults (3). Mice with a disrupted PRRX1 gene show perinatal death with craniofacial and limb malformations (4). Low PRRX1 expression levels were significantly associated with metastasis and poor prognosis of breast and colorectal cancer (5). |
Immunogen | Immunogen: PRRX1 antibody was raised against a 19 amino acid peptide near the center of human PRRX1. Buffer: PRRX1 antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [Paired related homeobox 1; homeobox protein PHOX1; Paired mesoderm homeobox protein 1; PHOX1; PMX1; PRX1; PRX-1; paired related homeobox 1], [PRRX1; PRRX1; PMX1; PRX1; AGOTC; PHOX1; PRX-1; PMX1; PRX-1] |
Gene, Accession # | [PRRX1], Gene ID: 5396, NCBI: NP_073207, UniProt: P54821 |
Catalog # | MBS153617 |
Price | $375 |
Order / More Info | PRRX1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |