CENPA Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | CENPA |
| Clone | polyclonal |
| Host Species | n/a |
| Reactive Species | human, rat |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Description: Rabbit IgG polyclonal antibody for Histone H3-like centromeric protein A(CENPA) detection. Tested with WB in Human;Rat. Background: Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. CENPA encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. And CENPA is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle. Alternative splicing results in multiple transcript variants encoding distinct isoforms. In higher eukaryotes, the recruitment of CENP-A nuc |
| Immunogen | Immunogen: E Coli-derived human CENPA recombinant protein (Position: M1-G140). Human CENPA shares 71.6% amino acid (aa) sequence identity with mouse CENPA. Ig Type: Rabbit IgG |
| Other Names | [Histone H3-like centromeric protein A; CENP A; CENP-A; cenpa; CENPA_HUMAN; Centromere autoantigen A; Centromere protein A 17kDa; Centromere protein A; Histone H3 like centromeric protein A; Histone H3-like centromeric protein A; centromere protein A], [CENPA; CENPA; CenH3; CENP-A; CENP-A] |
| Gene, Accession # | [CENPA], Gene ID: 1058, NCBI: NP_001035891.1, UniProt: P49450 |
| Catalog # | MBS178248 |
| Price | $280 |
| Order / More Info | CENPA Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Chueh AC, Wong LH, Wong N, Choo KH (January 2005). Variable and hierarchical size distribution of L1-retroelement-enriched CENP-A clusters within a functional human neocentromere. Hum. Mol. Genet. 14 (1): 85-93. 2. Folco HD, Pidoux AL, Urano T, Allshire RC (January 2008). Heterochromatin and RNAi are required to establish CENP-A chromatin at centromeres. Science 319 (5859): 94-7. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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