BBS5 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | BBS5 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: BBS5 antibody detects endogenous levels of BBS5. Function: The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier v |
| Immunogen | Immunogen: A synthesized peptide derived from human BBS5. Subcellular Location: Cell Projection, Cilium Membrane. Cytoplasm. Cytoplasm, Cytoskeleton, Cilium Basal Body. Cytoplasm, Cytoskeleton, Microtubule Organizing Center, Centrosome, Centriolar Satellite. Localizes to basal bodies. Predicted Cross Reactivity: Pig, Zebrafish, Bovine, Horse, Sheep, Chicken Similarity: Pig (100%), Zebrafish (92%), Bovine (100%), Horse (100%), Sheep (100%), Chicken (83%) |
| Other Names | [Bardet Biedl syndrome 5 protein; Bardet-Biedl syndrome 5 protein; BBS5; BBS5_HUMAN] |
| Gene, Accession # | [BBS5], Gene ID: 129880, NCBI: NP_689597.1, UniProt: Q8N3I7 |
| Catalog # | MBS9603258 |
| Price | $240, $280 |
| Order / More Info | BBS5 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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