RPTOR Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | RPTOR |
| Clone | [1411CT316.2.151.34] |
| Host Species | Mouse |
| Reactive Species | human, mouse, rat |
| Isotype | IgG1,k |
| Format | purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This RPTOR antibody is generated from a mouse immunized with recombinant protein. Involved in the control of the mammalian target of rapamycin complex 1 (mTORC1) activity which regulates cell growth and survival, and autophagy in response to nutrient and hormonal signals; functions as a scaffold for recruiting mTORC1 substrates. mTORC1 is activated in response to growth factors or amino acids. Growth factor-stimulated mTORC1 activation involves a AKT1- mediated phosphorylation of TSC1-TSC2, which leads to the activation of the RHEB GTPase that potently activates the protein kinase activity of mTORC1. Amino acid-signaling to mTORC1 requires its relocalization to the lysosomes mediated by the Ragulator complex and the Rag GTPases. Activated m |
| Immunogen | n/a |
| Other Names | [Regulatory-associated protein of mTOR; Raptor; p150 target of rapamycin (TOR)-scaffold protein; RPTOR; KIAA1303; RAPTOR] |
| Gene, Accession # | [RPTOR], Gene ID: 57521, NCBI: NP_001156506.1, UniProt: Q8N122 |
| Catalog # | MBS9200487 |
| Price | $165, $370 |
| Order / More Info | RPTOR Antibody from MYBIOSOURCE INC. |
| Product Specific References | Kim D.-H.,et al.Cell 110:163-175(2002). Hara K.,et al.Cell 110:177-189(2002). Zody M.C.,et al.Nature 440:1045-1049(2006). Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases. Nagase T.,et al.DNA Res. 7:65-73(2000). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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